Thyroid Lab Interpretation Guide
  • Home
  • About The Author
  • Primary Thyroid Lab Tests
    • TSH
    • Total T4
    • Free T4
    • Free T3
    • Reverse T3
    • TPO
    • Thyroglobulin Antibody
  • Secondary Thyroid Lab Tests
    • Thyroglobulin
    • TSI
    • TSH Receptor Antibody (TRaB)
    • SHBG
    • D3
    • Ferritin
    • Magnesium
    • Cortisol
    • Thyroid Cancer Monitoring
  • Worthless Thyroid Lab Tests
    • T3 Uptake
    • TBG
  • Poorman's Chart of Thyroid Metabolism
  • Contact
  • Resources & Links
  • Consult DR.T on your Lab Tests

TSH Receptor Antibody (TRaB)

                                                           TSH Receptor Antibody (TRaB)
                                             Produced by: Thyroid Infiltrating Lymphocytes
Definition / Purpose: Thyroid stimulating hormone receptor antibodies include two types of auto-antibodies that attach to proteins in the thyroid to which TSH normally binds (TSH receptors):
1. Thyroid stimulating immunoglobulin (TSI) binds to receptors and promotes the production of thyroid hormones, leading to hyperthyroidism.
2. Thyroid binding inhibitory immunoglobulin (TBII) blocks TSH from binding to receptors, blocking production of thyroid hormones and resulting in hypothyroidism.

Lab Reference Range: ≤16% Inhibition
When to order:
  • When ruling out the diagnosis of Graves or Hashimotos
Pearls:
Half-life: 90-125 days
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  • Home
  • About The Author
  • Primary Thyroid Lab Tests
    • TSH
    • Total T4
    • Free T4
    • Free T3
    • Reverse T3
    • TPO
    • Thyroglobulin Antibody
  • Secondary Thyroid Lab Tests
    • Thyroglobulin
    • TSI
    • TSH Receptor Antibody (TRaB)
    • SHBG
    • D3
    • Ferritin
    • Magnesium
    • Cortisol
    • Thyroid Cancer Monitoring
  • Worthless Thyroid Lab Tests
    • T3 Uptake
    • TBG
  • Poorman's Chart of Thyroid Metabolism
  • Contact
  • Resources & Links
  • Consult DR.T on your Lab Tests